Adding a certain compound to certain chemical reactions, such as: 139756-04-0, name is 1-Methyl-4-(2-propoxybenzamido)-3-propyl-1H-pyrazole-5-carboxamide, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 139756-04-0, Recommanded Product: 139756-04-0
3) 1-methyl-3-propyl-5 – (2-propoxy-phenyl) – 1,6-dihydro -7H-pyrazolo-[ 4,3-d] pyrimidin-7-one preparation: heating 6mmol compound 1-methyl-3-propyl-4 – (2-propoxy benzamido- ) pyrazole-5-carboxamide dissolved in 40 ml volume ratio (20-80): 1 ethanol in a mixture with hydrogen peroxide, add 6mmol naoh, stirring to dissolve, microwave heating 120 C reaction 25 minutes, after the reaction of the organic solvent is removed by reduced pressure distillation, the residue is distilled water washes, ethyl acetate extraction, organic subtraction-pressure distillation to remove the solvent, dried to obtain 1-methyl-3-propyl-5 – (2-propoxy-phenyl) – 1,6-dihydro -7H-pyrazolo-[ 4,3-d] pyrimidin-7-one, yield 85-90%;
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methyl-4-(2-propoxybenzamido)-3-propyl-1H-pyrazole-5-carboxamide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Guangdong Pharmaceutical University; CHEN, SIDONG; WANG, BAOGUO; MEI, WENJIE; ZHOU, JUNLI; JI, HENG; (20 pag.)CN103755709; (2016); B;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics