1145-01-3, Adding some certain compound to certain chemical reactions, such as: 1145-01-3, name is 3,5-Diphenyl-1H-pyrazole, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1145-01-3.
A solution of ethyl 3,5-diphenyl-1-hydro-pyrazole (0.20 mmol ), alpha-benzyl diazoacetoacetate ( 0.25 mmol) was added in a 2 5 mL Schrocker tube at room temperature.[Cp * RhCl2] 2 (0¡¤01 mmol), AgSbF6 (0.04 mmol) and tetrahydrofuran (2.00 mL) were added and argon was bubbled through argon for 2 minutes. Stir at 25 C for 48 hours. The reaction was stopped and concentrated under reduced pressure to give a crude product. Finally, the mixture was washed with a mixture of petroleum ether and ethyl acetate, and the corresponding nitrogen-containing fused heterocyclic compound (77 mg of white solid, 99% yield) was obtained by flash column chromatography (baby gel column).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1145-01-3.