Related Products of 92-43-3,Some common heterocyclic compound, 92-43-3, name is 1-Phenyl-3-pyrazolidinone, molecular formula is C9H10N2O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of CH2Cl2 (10 mL), H2SO4 (0.01 mol), intermediates 2 (0.01 mol) and KI (0.01 mol) was stirred at room temperature. Then, 30% H2O2 (0.02 mol) was added dropwise. The mixture was stirred at room temperature for 2 h and the product 3 directly crystallised from the CH2Cl2. Then 5% NaHSO3 (5 mL) was added to the mixture. The suspension was filtered off and washed, and the products were purifiedby recrystallisation from methanol.
The synthetic route of 92-43-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Liu, Jingjing; Yang, Shanguang; Dong, Ruimei; Jin, Zhudan; Wang, Mingliang; Journal of Chemical Research; vol. 42; 1; (2018); p. 24 – 27;,
Pyrazole – Wikipedia,
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