Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1120-82-7, name is (1H-Pyrazol-1-yl)methanol, A new synthetic method of this compound is introduced below., Recommanded Product: 1120-82-7
General procedure: Step 2: The reaction was performed under argon by using standard Schlenk techniques. To a cold (0?C) solution of 1-(2-hydroxymethyl)-3,5-dimethylpyrazole (1.0?g, 8?mmol) in chloroform was added dropwise thionyl chloride (1.15?mL in 15?mL of CHCl3) and the mixture was refluxed for 4?h. The precipitate (1-(2-chloromethyl)-3,5-dimethylpyrazole, 79% yield) was collected, washed with diethyl ether and dried.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Coelho, Felipe Lange; Dresch, Lucielle Codeim; Stieler, Rafael; Campo, Leandra Franciscato; Schneider, Paulo Henrique; Catalysis Communications; vol. 121; (2019); p. 19 – 26;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics