Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 141573-95-7, name is Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate
Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate 2 (5.1 g, 25 mmol) and KOH (1.68 g, 30 mmol) were added to water (50 mL). The mixture was stirred for overnight, then acidified to pH = 1 using HCl, to give 3 as a white solid that was filtered off and dried with yield 83%, m.p. 200-201 C (Ref. m.p. 204-205 C) [38] , 1H NMR (400 MHz, CDCl3), delta 3.91 (s, 3H, N-CH3), 7.19 (t, J = 54.2 Hz, 1H, -CHF2), 8.31 (s, 1H, pyrazolyl-H), 12.73 (s, 1H, -COOH).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 141573-95-7.
Reference:
Article; Liu, Xing-Hai; Zhao, Wen; Shen, Zhong-Hua; Xing, Jia-Hua; Xu, Tian-Ming; Peng, Wei-Li; European Journal of Medicinal Chemistry; vol. 125; (2017); p. 881 – 889;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics