Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 70817-26-4, name is (1-Phenyl-1H-pyrazol-4-yl)methanol, A new synthetic method of this compound is introduced below., SDS of cas: 70817-26-4
(1 -Phenyl- lH-pyrazol-4-yl)~methanol (2 g) in dichloromethane (15 mL) was treated with thionyl chloride (10 mL) and the mixture stirred at 200C for Ih. The resulting suspension was diluted with wA¸hexane (15 mL) and the solid collected by filtration to afford the subtitled compound as an off-white solid (1.120 g).1H NMR (400 MHz, CDCl3) I’ 8.61 (IH, s), 7.84 – 7.80 (3H, m), 7.53 – 7.47 (2H, m), 7.35 7.30 (IH, m), 4.77 (2H, s).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; ARGENTA DISCOVERY LIMITED; ASTRAZENECA AB; WO2009/153536; (2009); A1;,
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