Related Products of 400877-57-8,Some common heterocyclic compound, 400877-57-8, name is Methyl 1-methyl-4-nitro-1H-pyrazole-3-carboxylate, molecular formula is C6H7N3O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Methyl-4-nitro-lH-pyrazole-3-carboxylate (5.0 g, 27.01 mmol)Added to a hydrogenation reaction flask containing 50mL of methanol,Pd / C (10%, 0.5 g) was added,40psi hydrogen pressure reaction 1.0h,TLC test showed that the reaction was completed,Suction filtration, Pd / C filtration, and concentrated under reduced pressure to give the crude product (3.72 g, 88.7%),The crude product was used without purification in the next reaction administered.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Methyl 1-methyl-4-nitro-1H-pyrazole-3-carboxylate, its application will become more common.