Electric Literature of 33064-36-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 33064-36-7, name is 1H-Pyrazole-3-carboxamide belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
General procedure: A flask was charged with t-butyl lH-pyrazole-3-carboxylate (2.42 g, 14.4 mmol, 1.00 equiv), DCM (20 mL), 4-nitrophenyl chloroformate (2.90 g, 14.4 mmol, 1.00 equiv), and triethylamine (4.36 g, 43. 1 mmol, 3.00 equiv). The resulting solution was stirred for 3 h at room temperature and concentrated under reduced pressure to provide 4.80 g (crude) of 3-(t-butyl) l-(4- nitrophenyl) lH-pyrazole-l,3-dicarboxylate as a yellow oil. LCMS (ESI, m/z): 334 [M+H]+.
The synthetic route of 1H-Pyrazole-3-carboxamide has been constantly updated, and we look forward to future research findings.