Electric Literature of 1780-72-9, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1780-72-9 as follows.
General procedure: To a mixture of 1-aryl-3-ethoxy-2-(phenylsulfonyl)prop-2-en-1-one 3refPreviewPlaceHolder[28] (10 mmol) and appropriate aminopyrazole derivative 2 (10 mmol) in absolute EtOH (25 mL) were added few drops of piperidine and the reaction mixture was refluxed for 1 h, then left to cool. The formed solid product was filtered off, washed with ethanol and recrystallized from EtOH/DMF to afford products identical in all respects (mp, mixed mp and spectra) with those obtained by refPreviewPlaceHolderMethod A above.
According to the analysis of related databases, 1780-72-9, the application of this compound in the production field has become more and more popular.