Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 31108-57-3, name is 1H-Pyrazole-4-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows., Safety of 1H-Pyrazole-4-carbonitrile
To a solution of crude reactant SC-II (100 mg, 0.241 mmol) in anhydrous THF (5 mL) was added lH-pyrazole-4-carbonitrile (112 mg, 1.2 mmol) followed by potassium carbonate (170 mg, 1.2 mmol) and the solution was heated at 60 C for 2h. Then the reaction mixture was diluted with ethyl acetate (100 mL). The resulting solution was washed with brine (2×50 mL), dried over magnesium sulfate and concentrated in vacuo. The crude product was purified by reverse phase prep-HPLC to afford product SB-21 (46 mg, 0.109 mmol, Yield=45%) as a white solid. 1HNMR (500 MHz, CDC13) 5(ppm): 7.86 (IH, s), 7.81 (IH, s), 5.00 (IH, AB), 4.92 (IH, AB), 2.61 (IH, t), 0.67 (3H, s), 0.67-2.25 (24H, m). LCMS: rt=2.47 mm, /z=424.2 [M+H]+
According to the analysis of related databases, 31108-57-3, the application of this compound in the production field has become more and more popular.