Some common heterocyclic compound, 21230-50-2, name is 3-Amino-1-methyl-1H-pyrazole-4-carbonitrile, molecular formula is C5H6N4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. category: pyrazoles-derivatives
General procedure: Carbonitriles 7-10 (0.03 mol) was dissolved in 7 mL concdH2SO4 at 0 C and stirred at room temperature for 5 h. Then thereaction mixture was poured into ice cold water and neutralizedto pH 7 with 28% NH3 solution. The white precipitate was formedwhich was further washed with cold water and dried undervacuum.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 21230-50-2, its application will become more common.