Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 51985-95-6, name is Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 51985-95-6
c) l-Methyl-5-(5-methyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-lH-pyrazole-3-carboxylic acid methyl esterTo a stirred solution of 5 -hydroxy- 1 -methyl- lH-pyrazole-3-carboxylic acid methyl ester (400 mg, 2.6 mmol) and (5-methyl-3-pyridin-2-yl-isoxazol-4-yl)-methanol (500 mg, 2.6 mmol) inTHF(10 mL) at 5 0C under argon was added triphenylphosphine (862 mg, 3.3 mmol), then diethyl azodicarboxylate (573 mg, 3.3 mmol) was added dropwise. The reaction mixture was warmed to room temperature and stirred overnight. The reaction mixture was then evaporated. Purification by chromatography (silica, dichloromethane: methanol = 9:1) then purification using a 5 x 50 cm Chiralpak AD column at room temperature using an isopropanol:heptane (2:8) mobile phase with UV detection at 220 nM afforded the title compound (400 mg, 48percent) as a white solid. MS: m/e = 328.3 [M+H]+.
According to the analysis of related databases, 51985-95-6, the application of this compound in the production field has become more and more popular.