Electric Literature of 13808-62-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 13808-62-3, name is 4-Methyl-3-phenyl-1H-pyrazole belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
Alternate Synthesis for alpha-ethyl-N,N,4-trimethyl-3-phenylpyrazole-1-acetamide Sodium methoxide powder (216 g., 4.0 mole) was added over 10 minutes at a stirred solution of 4-methyl-3-phenylpyrazole (632 g., 4.0 mole) in tetrahydrofuran (1.0 liter) at 10 C. 2-Bromo-N,N-dimethylbutyramide (911 g., 4.7 mole) was added dropwise over 30 minutes while maintaining the temperature of the reaction solution below 30 C. by external cooling. The solution was stirred for an additional 30 minutes at room temperature, and the THF was then removed under reduced pressure. The residual oil was partitioned between chloroform and water. The chloroform layer was evaporated and the residual oil was recrystallized from benzene:Skellysolve B to give 772 g. of alpha-ethyl-N,N,4-trimethyl-3-phenylpyrazole-1-acetamide, m.p. 85.5-87.5 C. Evaporation of the crystallization mother liquors gave 365 g. of oil containing additional product.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Methyl-3-phenyl-1H-pyrazole, other downstream synthetic routes, hurry up and to see.