Related Products of 3920-40-9, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.
A mixture of 2-bromothiazole-4-carboxylic acid (891 mg), 4-amino-1-methyl-1H-pyrazole-3-carboxamide (600 mg) and HATU (1.95 g) in DMF (5 ml) and ethyldiisopropylamine (1.5 ml) is stirred at room temperature for 20 h and then poured into ice-water. The precipitated solid is filtered off, washed twice with water and three times each with diethyl ether and ethyl acetate and dried in vacuo (889 mg).C9H8BrN5O2S (329.0), LC-MS (ZQ): Rt=0.87, m/z=330 [M+H]+. 1H-NMR (300 MHz, D6-DMSO): 3.88 (s, 3H), 7.45 (br. s., 1H), 7.70 (br. s., 1H), 8.31 (s, 1H), 8.41 (s, 1H), 11.0 (s, 1H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, other downstream synthetic routes, hurry up and to see.