Related Products of 35344-95-7,Some common heterocyclic compound, 35344-95-7, name is 1H-Pyrazole-4-carbaldehyde, molecular formula is C4H4N2O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: To a solution of the aldehyde (1 equiv.) and amine (1 equiv.) in methanol was added a catylytic amount of glacial acetic acid (a few drops) and the contents were stirred at 25 ¡ãC as outlined in reaction Scheme 1. After 4 h, the methanol was removed under reduced pressure and the crude aldimine J_a was used in the next step without further purification.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1H-Pyrazole-4-carbaldehyde, its application will become more common.