Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 50-33-9, Name is Phenylbutazone, SMILES is O=C(C1CCCC)N(C2=CC=CC=C2)N(C3=CC=CC=C3)C1=O, belongs to pyrazoles-derivatives compound. In a document, author is Sharma, Shubham, introduce the new discover, Quality Control of Phenylbutazone.
Transition-Metal-Free C-S Bond Forming Strategy towards Synthesis of Highly Diverse Pyrazole Tethered Benzothiazoles: Investigation of their Photophysical Properties
A metal-free domino approach has been devised towards construction of two C-S bonds for the synthesis of bioactive N, S-heterocycles. The developed method was extended for the preparation of structurally diverse pyrazole tethered benzothiazole frameworks by using one-pot operation of pyrazole C-3/4/5 carbaldehydes, electron rich aromatic amines and elemental sulfur. This protocol provides excellent fluorophores with several additional advantages such as transition metal-free approach, inexpensive and odorless sulfur source, superior atom economy, and broad substrate scope including gram scale synthesis. The synthesized pyrazole tethered benzothiazole fluorophores were evaluated for their luminescent properties including absorbance, excitation, emission, molar extinction coefficient, brightness, and Stokes shift. The photophysical studies revealed that these pyrazole and benzothiazole hybrids emerged as excellent fluorophores and could exhibit fluorescence quantum yield up to 66%.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 50-33-9 is helpful to your research. Quality Control of Phenylbutazone.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics