Electric Literature of 1985-46-2, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 1985-46-2, Name is N2,N2-Dimethyl-1,3,5-triazine-2,4,6-triamine, SMILES is NC1=NC(N)=NC(N(C)C)=N1, belongs to pyrazoles-derivatives compound. In a article, author is Jadhav, Satish B., introduce new discover of the category.
DESIGN, SYNTHESIS AND IN-VITRO ANTI-INFLAMMATORY, ANTIMICROBIAL ACTIVITIES OF SOME NOVEL MANNICH BASES OF PYRAZOLE-1-CARBOTHIOAMIDE DERIVATIVES
A novel series of Mannich Bases of Pyrazole-1-Carbothioamide Derivatives (7a-g) was synthesized by first cyclocondensation of chalcones (3a-g) with thiosemicarbazide to obtained 5-(6-methoxynaphthalen-1-yl)-3-(Substituted phenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide(5a-g), which further refluxed with 4-chloroaniline (6) and formaldehyde in methanol for 6-10 hrs. to afford Mannich Bases of Pyrazole-1-Carbothioamide derivatives i.e. 4-(((4-chlorophenyl)amino)methyl)-5-(6-methoxynaphthalen-1-yl)-3-(Substituted phenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide (7a-g). The structural identification of products is reported by IR and H-1-NMR spectral data as well as analytical and physical data and also the synthesized compounds were screened for their in-vitro anti-inflammatory and antimicrobial activity.
Electric Literature of 1985-46-2, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 1985-46-2.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics