One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 1453-58-3, Name is 3-Methylpyrazole, formurla is C4H6N2. In a document, author is Yunusova, Sevilya N., introducing its new discovery. Recommanded Product: 3-Methylpyrazole.
Iodonium salts as efficient iodine(iii)-based noncovalent organocatalysts for Knorr-type reactions
Hypervalent iodine(iii)-derivatives display higher catalytic activity than other aliphatic and aromatic iodine(i)- or bromine(i)-containing substrates for a Knorr-type reaction of N-acetyl hydrazides with acetyl acetone to give N-acyl pyrazoles. The highest activity was observed for dibenziodolium triflate, for which 10 mol% resulted in the generation of N-acyl pyrazole from acyl hydrazide and acetyl acetone typically at 50 degrees C for 3.5-6 h with up to 99% isolated yields. H-1 NMR titration data and DFT calculations indicate that the catalytic activity of the iodine(iii) is caused by the binding with a ketone.
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Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics