Let¡¯s face it, organic chemistry can seem difficult to learn, Recommanded Product: Phenylbutazone, Especially from a beginner¡¯s point of view. Like 50-33-9, Name is Phenylbutazone, molecular formula is pyrazoles-derivatives, belongs to pyrazoles-derivatives compound. In a document, author is Apte, Chirag N., introducing its new discovery.
Grafting Bis(heteroaryl) Motifs into Ring Structures
Here we demonstrate an approach to graft bis(heteroaryl)-containing motifs into ring structures. The process occurs by redirecting a previously reported oxadiazole-forming reaction towards a pyrazole-forming process affording pyrazolyl-azole containing molecules. Through the use of (N-isocyanimino)phosphorane (Pinc), heteroatom-rich fused tricyclic heterocycles can be synthesized in a single step from readily accessible starting materials. The cyclization of peptides results in macrocycles that feature bis(heteroaryl) motifs with uncommon connectivity as compared to their natural counterparts.
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Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics