Synthetic Route of 5744-40-1, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 5744-40-1 as follows.
A suspension of Step 1 intermediate (5.3 g, 31.52 mmol) in aqueous sodium hydroxide (5%, 32 mL) was refluxed for 4 h. The reaction mixture was cooled to 0 C and acidified with cone. HQ till pH 2-3. The precipitated solid was filtered and dried well to obtain 3.67 g of the desired product. lH NMR (300 MHz, CDC13): delta 3.87 (s, 3H), 4.13 (s, 3H), 6.61 (s, 1H), 6.71 (s, 1H).
According to the analysis of related databases, 5744-40-1, the application of this compound in the production field has become more and more popular.