Application of 25016-17-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25016-17-5, name is Methyl 5-methyl-1H-pyrazole-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows.
b) Method for svnthesising the pyrazolecarboxylic acid ED-2b (synthesis method B)ED-5a (2.00 g, 14.3 mmol) in DMF (7 mL) is added dropwise to a suspension of NaH (694 mg, 60 %, 17.4 mmol) in anhydrous DMF (8 mL) while cooling with ice and the mixture is slowly thawed to RT over 1 h. Then isopropyl bromide (2.7 mL, 28.8 mmol) is added and the mixture is stirred for 20 h at RT. The reaction mixture is mixed with a little water, then for saponification aqueous LiOH solution (414 mg in 3 mL H20) is added and the mixture is stirred for 2 h at 40C. The reaction mixture is neutralised with hydrochloric acid, evaporated down to some extent using the rotary evaporator and the residue is purified by preparative RP-MPLC. The product-containing fractions of ED-2b (HPLC-MS: tRet. = 0.00 min; MS (M-H)” = 167) are combined and freeze-dried.
The chemical industry reduces the impact on the environment during synthesis Methyl 5-methyl-1H-pyrazole-3-carboxylate. I believe this compound will play a more active role in future production and life.