Related Products of 127107-23-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 127107-23-7, name is 1-Methyl-1H-pyrazol-4-amine hydrochloride, This compound has unique chemical properties. The synthetic route is as follows.
4- ( (IS, 2R) -2- ( (tert-Butoxycarbonyl) amino) cyclopropyl) -5- methylthiophene-2-carboxylic acid (3.06 g) , 1-methyl.-1H- pyrazol-4-amine hydrochloride (1.37 g) and triethylamine (5.73 mL) were dissolved in DMF (30 mL) , 0- (7-azabenzotriazol-l-yl) – Nu,Nu,Nu’ ,Nu’ -tetramethyluronium hexafluorophosphate (4.69 g) was added, and the mixture was stirred at 40C overnight. Water was added to the reaction mixture, and the mixture wasextracted with ethyl acetate. The extract was washed with saturated aqueous sodium hydrogen carbonate solution, water and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane/ethyl acetate and methanol/ethyl acetate) to give the title compound (3.7 g) .MS: [M+H]+377.1
The chemical industry reduces the impact on the environment during synthesis 1-Methyl-1H-pyrazol-4-amine hydrochloride. I believe this compound will play a more active role in future production and life.