Some common heterocyclic compound, 180207-57-2, name is 2-(1H-Pyrazol-4-yl)ethanol, molecular formula is C5H8N2O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 180207-57-2
A mixture ofthionyl chloride (6.318 g, 53.55 mmol) and 2-(1H-pyrazol-4-yl)ethan-1-ol (2.0 g, 17.85 mmol) washeated to 70″C for 15 minutes. The reaction mixture was concentrated under reduced pressure, the residuewas triturated with ethanol/diethyl ether to the title compound (2.3 g, 98%) as an off-white solid.LC-MS (method 6): Rt = 1.61 min; m/z = 131.06 (M+H+).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 180207-57-2, its application will become more common.