A new synthetic route of 75415-03-1

According to the analysis of related databases, 75415-03-1, the application of this compound in the production field has become more and more popular.

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 75415-03-1 as follows. Recommanded Product: 2-(1H-Pyrazol-3-yl)pyridine

General procedure: Compound 4a (2 mmol), NaH (2.4 mmol) and indole were dissolved in DMF (10 mL). The reaction mixture was stirred at room temperature for 12h before diluted with water (20 mL) and extracted with ethyl acetate (30 mL ¡Á 3). The organic layer was concentrated in vacuum. Purication by ash column chromatography gave the target product 5h.

According to the analysis of related databases, 75415-03-1, the application of this compound in the production field has become more and more popular.