Zhu, Hualing published the artcileSynthesis, structure and biological activities of phenylmethylacylpyrazolinone derivatives modified with glycylglycine methyl ester, Quality Control of 4551-69-3, the publication is Youji Huaxue (2013), 33(12), 2631-2636, database is CAplus.
Four new 1-phenyl-3-methyl-4-acyl-2-pyrazolin-5-one derivatives modified with glycylglycine Me ester were synthesized and characterized by UV, 1H NMR, 13C NMR, IR, elemental anal. The mol. structure of compound I was also characterized by single-crystal X-ray diffraction. The anal. results showed that new compounds existed in enamine-ketone forms. The antibacterial activity tests of the compounds at different concentrations against E. coli and Bacillus subtilis were performed using disk diffusion method. The results indicated that most compounds had weak abilities of inhibiting the growth of the two bacteria, and the inhibiting abilities of 4-aryl compounds were better. The herbicidal activity tests of the compounds against wheat and rape were performed by plate culture method. The results indicated that all compounds had the abilities of inhibiting the growth of the two plants, and the inhibiting abilities of the compounds against rape were better, especially the inhibiting abilities to the growth of rapeseed radicle almost reached completely suppressed.
Youji Huaxue published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C7H8O3, Quality Control of 4551-69-3.
Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics