Xu, Peng published the artcileNovel pleuromutilin derivatives with excellent antibacterial activity against Staphylococcus aureus, Safety of 3-Isobutyl-1-methyl-1H-pyrazole-5-carboxylic acid, the main research area is pleuromutilin derivative antibacterial activity Staphylococcus.
Ten novel pleuromutilin derivatives with thioether moiety and heterocyclic carboxamide or chloroformate group in the side chain were synthesized and confirmed by 1H NMR, IR and HRMS. The results of the antibacterial activity showed that the title compounds had excellent antibacterial activity against Staphylococcus aureus, among which the MIC of 5f reached 0.03125 μg/mL.
Chemical Biology & Drug Design published new progress about Antibacterial agents. 769132-77-6 belongs to class pyrazoles-derivatives, name is 3-Isobutyl-1-methyl-1H-pyrazole-5-carboxylic acid, and the molecular formula is C9H14N2O2, Safety of 3-Isobutyl-1-methyl-1H-pyrazole-5-carboxylic acid.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics