Bulychev, Yu. N.’s team published research in Khimiya Geterotsiklicheskikh Soedinenii in 1988 | CAS: 15366-34-4

Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. The application of pyrazole derivatives in the development of anticancer agents has been thoroughly investigated and verified. Moreover, the medicinal features of a number of natural products incorporating pyrazole moiety such as pyrazofurin, pyrazofurin B, pyrazole-3(5)-carboxylic acid and 4-methylpyrazole-3(5)-carboxylic acid have been reported.SDS of cas: 15366-34-4

In 1988,Bulychev, Yu. N.; Preobrazhenskaya, M. N.; Chernyshev, A. I.; Esipov, S. E. published 《N-Alkylation of substituted pyrazoles and pyrazolo[3,4-d]pyrimidines by dimethylformamide diethyl acetal or orthoformate》.Khimiya Geterotsiklicheskikh Soedinenii published the findings.SDS of cas: 15366-34-4 The information in the text is summarized as follows:

Alkylating pyrazolecarboxylate I (R = R1 = H) by DMF di-Et acetal or HC(OEt)3 gives mixtures containing 41 and 38% I (R = Et, R1 = H) and 36 and 23% I (R = H, R1 = Et), resp. Similarly, alkylation of pyrazolopyrimidine II (R2 = MeS, R3 = H) gave 60 and 43% III, resp. Addnl. obtained were III (R2 = R3 = MeS, EtS; R2 = EtO, MeS). The results came from multiple reactions, including the reaction of Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4SDS of cas: 15366-34-4)

Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. The application of pyrazole derivatives in the development of anticancer agents has been thoroughly investigated and verified. Moreover, the medicinal features of a number of natural products incorporating pyrazole moiety such as pyrazofurin, pyrazofurin B, pyrazole-3(5)-carboxylic acid and 4-methylpyrazole-3(5)-carboxylic acid have been reported.SDS of cas: 15366-34-4

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics