Category: 75415-03-1

Related Products of 75415-03-1, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 75415-03-1 as follows.

1st step: adding to the reaction kettle 2.1g2 – (1H-pyrazol-3-yl) pyridine and 3.7g2- bromopyridine [2 – (1H-pyrazol-3-yl) pyridine and 2-polybromide pyridine mole ratio of 1 : 1.6], in the reactor is placed into an oven after heating to 190 C, reaction 24h;2nd step: after the reaction is ended, take the solid using saturated Na2CO3solution cleaning, separating out the solid;3rd step: the separate the solid is dried fully then dissolved in chloroform, using silica gel as stationary phase, the volume of the petroleum ether and ethyl acetate ratio of 1:1 as the eluting agent mixed solution of dry-column, collecting product, evaporation and concentration, drying, the obtained yellow solid powder is the target product, nuclear product resonating chart as shown in Figure 1, the yield of 70.1%. The eluting agent is added before the dissolving solid petroleum ether for use out of the chloroform solution. he basic steps of the embodiment 1 the same, but in 1st step 2 – (1H-pyrazol-3-yl) pyridine and 2-bromo pyridine molar ratio of 1 : 1.5, the heating temperature is 180 C, the reaction time is 30h, saturation, solid in 2nd step NaHCO3solution cleaning, the obtained yield of 71.0%.

According to the analysis of related databases, 75415-03-1, the application of this compound in the production field has become more and more popular.

Related Products of 75415-03-1,Some common heterocyclic compound, 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine, molecular formula is C8H7N3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A mixture of CuCl2¡¤4H2O (20.84 mg, 0.1 mmol), Hpzpy(28.84 mg, 0.2 mmol), DMF (3 mL) and H2O(1 mL) wassealed in a 25-ml Teflon-lined stainless container and heatedat 130 C for 72 h. After cooling to room temperature at arate of 5 C/h, colorless block crystals were obtained in ca.62% yield based on Cu. Anal. Calcd. for C18H18Cu2N6O6:C 39.93%, H 3.35%, N 15.52%; found C 39.84%, H 3.24%,N 15.48%. IR (KBr, cm-1): 3138 w, 2040 s, 1584 s, 1512 w,1438 m, 1372 w, 1245 w, 1089 s, 1028 w, 777 m, 723 m,705 w, 692 w, 623 m.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-(1H-Pyrazol-3-yl)pyridine, its application will become more common.

Related Products of 75415-03-1, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 75415-03-1 as follows.

General procedure: Compound 4a (2 mmol), NaH (2.4 mmol) and indole were dissolved in DMF (10 mL). The reaction mixture was stirred at room temperature for 12h before diluted with water (20 mL) and extracted with ethyl acetate (30 mL ¡Á 3). The organic layer was concentrated in vacuum. Purication by ash column chromatography gave the target product 5h.

According to the analysis of related databases, 75415-03-1, the application of this compound in the production field has become more and more popular.

Adding a certain compound to certain chemical reactions, such as: 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 75415-03-1, Formula: C8H7N3

CuCl2 ¡¤ 2H2O, 2- (1H-pyrazol-3-yl) pyridine in a molar ratio of 1: 0.5Were added to the reactor liner,And add 17ml of acetone to the reactor tank, sealed,The reaction at a temperature of 160 72h. Naturally cooled to room temperature,Get the chemical formula C16H12N6C14Cu2 crystal, yield:70% (calculated as CuCl2 ¡¤ 2H2O).After the complex is excited by the light of lambdaex = 325nm,A strong characteristic fluorescence appears at lambdaem = 365 nm.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-(1H-Pyrazol-3-yl)pyridine, and friends who are interested can also refer to it.

Electric Literature of 75415-03-1,Some common heterocyclic compound, 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine, molecular formula is C8H7N3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: A mixture of 2,3′,5,5′-biphenyl tetracarboxylic acid (33.0 mg,0.1 mmol), 2,2′-bipy (17.6 mg, 0.1 mmol), Cd(OAc)2*2H2O(26.6 mg, 0.1 mmol), and KOH (5.6 mg, 0.1 mmol) were added to water (12 mL) in a 25 mL Teflon-lined stainless steel vessel. Themixture was heated at 413 K for 3 days, and then slowly cooled down to room temperature. Colorless block crystals of 2 were obtained (yield: 47% based on cadmium). Anal. Calc. for C36H26Cd2-N4O10: C, 48.07; H, 2.91; N, 6.23. Found: C, 48.16; H, 2.87; N, 6.29%.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-(1H-Pyrazol-3-yl)pyridine, its application will become more common.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine, A new synthetic method of this compound is introduced below., category: pyrazoles-derivatives

HL (0.2 mmol, 29 mg), Cu(NO3)23H2O (0.2 mmol,48 mg), 4,4?-dibromobiphenyl (0.01 mmol, 31 mg), ethanol (3 ml) were added to 12 ml H2O, subsequently, the mixture wasplaced in a Teflon-lined stainless reactor and heated to 140 C for 3 days under autogenous pressure. Finally, the blue blockshapedcrystals suitable for X-ray single crystal diffraction were obtained with a yield of 32.7 % (based on Cu(NO3)23H2O)

The synthetic route of 75415-03-1 has been constantly updated, and we look forward to future research findings.

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 75415-03-1 as follows. Recommanded Product: 2-(1H-Pyrazol-3-yl)pyridine

General procedure: Compound 4a (2 mmol), NaH (2.4 mmol) and indole were dissolved in DMF (10 mL). The reaction mixture was stirred at room temperature for 12h before diluted with water (20 mL) and extracted with ethyl acetate (30 mL ¡Á 3). The organic layer was concentrated in vacuum. Purication by ash column chromatography gave the target product 5h.

According to the analysis of related databases, 75415-03-1, the application of this compound in the production field has become more and more popular.

75415-03-1, A common compound: 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine, belongs to pyrazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.

General procedure: Compound 4a (2 mmol), NaH (2.4 mmol) and indole were dissolved in DMF (10 mL). The reaction mixture was stirred at room temperature for 12h before diluted with water (20 mL) and extracted with ethyl acetate (30 mL ¡Á 3). The organic layer was concentrated in vacuum. Purication by ash column chromatography gave the target product 5h.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(1H-Pyrazol-3-yl)pyridine, other downstream synthetic routes, hurry up and to see.