Tag: M.W=200-250

Desai, C. K. published the artcileSynthesis of azo dyes using 4-amino-2,4′-dichlorodiphenyl ether and their application on wool, nylon and silk fibres, Category: pyrazoles-derivatives, the publication is Oriental Journal of Chemistry (1999), 15(2), 381-382, database is CAplus.

New azo acid dyes using 4-amino-2,4′-dichlorodiphenyl ether as the diazo component and pyrazolones as the coupling components were synthesized. The dyes were characterized by elemental anal. and IR spectra. The dyeing properties on various textile fabrics were investigated. The dyes were water soluble and applied at 90-100°C on cotton, silk, nylon, and wool.

Oriental Journal of Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Category: pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Mehta, K. H. published the artcileSynthesis of new heterocyclic thiazolidinone and azetidinone compounds and their antibacterial activity, Name: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Asian Journal of Chemistry (2003), 15(1), 459-465, database is CAplus.

Thiazolidinones and azetidinones have been prepared by the reaction of various Schiff bases with thioglycolic acid and chloroacetyl chloride resp. The target compounds included methylenebis(4,1-phenylene)bis[9-thia-1,2,6-triazaspiro[4.4]non-2-en-7-one] derivatives I (R = Me, CO₂H; R¹ = H, Cl; R² = H, Cl, SO₃H; R³ = H, SO₃H; R⁴ = H, Cl, SO₃H) and methylenebis(4,1-phenylene)bis[1,5,6-triazaspiro[3.4]oct-6-en-2-one] derivatives II (R = Me, CO₂H; R¹ = H, Cl; R² = H, Cl, SO₃H; R³ = H, SO₃H; R⁴ = H, Cl, SO₃H). The structures of the compounds have been confirmed by elemental anal. and spectral anal. The antibacterial activity of the compounds has also been screened.

Asian Journal of Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Name: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Naik, R. D. published the artcileSynthesis of azo dyes using 2-amino-4,4′-dichlorodiphenyl ether 2′-sulfonic acid and their application on wool, nylon and silk as acid dyes, SDS of cas: 14580-22-4, the publication is Oriental Journal of Chemistry (1997), 13(3), 313-314, database is CAplus.

2-Amino-4,4′-dichloro-2′-sulfodiphenyl ether was diazotized and coupled with pyrazolone derivatives, γ Acid, or H Acid to give azo dyes that were used to dye wool, nylon, and silk. The fastness of the dyes to light and washing was tested.

Oriental Journal of Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, SDS of cas: 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Desai, Krunal G. published the artcileMicrowave enhanced heterocyclization: A convenient procedure for antimicrobial 1,5-benzothiazepine compounds, SDS of cas: 14580-22-4, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2007), 46B(7), 1179-1186, database is CAplus.

A series of 2,5-dihydro-4-[1-(2-chlorophenyl)-3-methyl-5-pyrazolylidenamino]-2-aryl-1,5 benzothiazepines I [R = Ph, 2-HOC₆H₄, 3-O₂NC₆H₄, 2-ClC₆H₄, 4-ClC₆H₄, 4-Me₂NC₆H₄, 4-MeOC₆H₃-3-OH, 3,4,5-(MeO)₃C₆H₂, 3-PhOC₆H₄, 4-MeOC₆H₄] was synthesized by an environmentally benign procedure, and they were evaluated for their antimicrobial activity. On microwave irradiation (MWI) under solvent-free conditions, neat reactants resulted in enhancement of yields and reaction rates. Structures of the synthesized compounds were elucidated on the basis of elemental anal. and spectra. The compounds showed moderate antibacterial and antifungal activity.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, SDS of cas: 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Arriau, J. published the artcileStudy by semiempirical methods on theoretical chemistry in the pyrazolone series. IV. Substituted derivatives of 1-phenyl-3-methylpyrazol-5-one, HPLC of Formula: 14580-22-4, the publication is Tetrahedron (1972), 28(23), 5725-38, database is CAplus.

The electronic spectrum of 1-phenyl-3-methylpyrazol-5-one was calculated by the semiempirical MO methods of complete neglect of differential overlap, Pariser-Parr-Pople, and Hueckel-ω. At long wavelengths the Ph groups gave 2 relatively weak bands, the pyrazolone ring showed an intense transition, and another strong band, only observed exptl. in solvents such as n-heptane, occurred at short wavelengths. Substituents in the Ph group influenced the spectra according to their nature and position. The effect of solvent was estimated quant.

Tetrahedron published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, HPLC of Formula: 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Trivedi, Amit published the artcileFacile one-pot synthesis and antimycobacterial evaluation of pyrazolo[3,4-d]pyrimidines, Application In Synthesis of 14580-22-4, the publication is Archiv der Pharmazie (Weinheim, Germany) (2008), 341(7), 435-439, database is CAplus and MEDLINE.

The present article describes a facile one-pot synthesis of a series of eight pyrazolo[3,4-d]pyrimidines I (R = H, 2-Cl, 3-Cl, 4-Me, 3-SO₃H, 4-SO₃H, etc.) which were evaluated for their in-vitro antibacterial activity against Mycobacterium tuberculosis H37Rv using the Alamar-Blue susceptibility test and the activity expressed as the min. inhibitory concentration (MIC) in mg/mL. The compounds I (R = 2-Cl, 3-Cl, 4-Me) and II exhibited the best results (1.2 μg/mL) when compared with first-line drugs such as isoniazid (INH) and rifampicin (RIP). Therefore, this class of compounds could be a good starting point to develop new lead compounds in the treatment of multidrug-resistant tuberculosis.

Archiv der Pharmazie (Weinheim, Germany) published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C7H8BFO2, Application In Synthesis of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Li, Li-Xia published the artcileDirect sulfonylation of pyrazolones with sodium sulfinates catalyzed by TBAI in water, Related Products of pyrazoles-derivatives, the publication is Tetrahedron Letters (2018), 59(15), 1517-1520, database is CAplus.

An efficient sulfonylation reaction of pyrazolones with sodium sulfinates catalyzed by TBAI was established. A wide variety of valuable sulfonated pyrazolones were obtained in good to excellent yields using water as solvent.

Tetrahedron Letters published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Related Products of pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Khan, Misbahul Ain published the artcilePyranopyrazoles. II. Synthesis and reactions of 1H,6H-pyrano[2,3-c]pyrazol-6-ones, Computed Properties of 14580-22-4, the publication is Journal of Heterocyclic Chemistry (1982), 19(5), 1077-85, database is CAplus.

Pyranopyrazolones I [R = H, Me, (un)substituted Ph; R¹, R² = Me, Ph; R³ = H] were prepared by treating R¹COCH₂CO₂Et with RNHNH₂ or II. Nitration, chlorination, and bromination of these pyranopyrazolones gave I (R³ = NO₂, Cl, Br). The substitution products are formed by addition-elimination.

Journal of Heterocyclic Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Computed Properties of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Liu, Xiaoxia published the artcileMetal-free direct construction of sulfenylated pyrazoles via the NaOH promoted sulfenylation of pyrazolones with aryl thiols, Application of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is RSC Advances (2016), 6(57), 51830-51833, database is CAplus.

A convenient and cost-effective NaOH-promoted direct sulfenylation of pyrazolones with aryl thiols has been developed under mild and metal-free conditions. In this transformation, a range of valuable sulfenylated pyrazoles can be easily achieved in moderate to excellent yields, with high atom efficiency and good functional group tolerance.

RSC Advances published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Application of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Wei, Wei published the artcileMetal-free molecular iodine-catalyzed direct sulfonylation of pyrazolones with sodium sulfinates leading to sulfonated pyrazoles at room temperature, Safety of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Organic Chemistry Frontiers (2017), 4(1), 26-30, database is CAplus.

A simple and convenient mol. iodine-catalyzed direct sulfonylation of pyrazolones with sodium sulfinates has been developed in the presence of TBHP at room temperature This methodol. can allow for the synthesis of a series of valuable sulfonated pyrazoles, e.g., I in good to excellent yields simply using readily-available starting materials without requiring any metal or cryogenics.

Organic Chemistry Frontiers published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C11H10O, Safety of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics