《Solubility of Water in Aprotic Heterocyclic Anion (AHA) Ionic Liquids》 was written by Avelar Bonilla, Gabriela M.; Morales-Collazo, Oscar; Brennecke, Joan F.. Product Details of 20154-03-4This research focused onwater solubility LLE aprotic tetraalkylphosphonium ionic liquid heterocyclic anion. The article conveys some information:
The hydrophobic-hydrophilic character of a series of 15 tetra-alkylphosphonium ionic liquids with aprotic heterocyclic anions (AHAs) was studied by measuring their liquid-liquid equilibrium with water. Specifically, the solubility of water in the ionic-liquid-rich phase was determined at room temperature by Karl Fischer titration The effect of the tetra-alkyl-phosphonium cation was studied by varying the alkyl chain length; as expected, hydrophobicity increases with increasing alkyl chain length. The effect of the anion was studied by pairing the tetra-alkyl-phosphonium cation with different AHAs and by adding different substituents on the anion. The anion nature, basicity, and electron withdrawing effect of different substituents proved to have a significant impact on the IL’s hydrophobicity. Changes in the alkyl chain length of the cation and the nature of the anion are able to tune the solubility of water in the ILs over an order of magnitude. After reading the article, we found that the author used 3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4Product Details of 20154-03-4)
3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Product Details of 20154-03-4
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics