Liu, Haidong; Ge, Liang; Wang, Ding-Xing; Chen, Nan; Feng, Chao published the artcile< Photoredox-Coupled F-Nucleophilic Addition: Allylation of gem-Difluoroalkenes>, Safety of 1-(4-Bromophenyl)-1H-pyrazole, the main research area is homoallylic trifluoromethane preparation; gem difluoroalkene photoredox coupled fluoroallylation; allylic compounds; fluorine; photochemistry; radicals; reaction mechanisms.
A novel strategy for the expedient construction of CF3-embeded tertiary/quaternary carbon centers was developed by taking advantage of photoredox catalysis. Thanks to a key step of single-electron oxidation, electron-rich gem-difluoroalkenes, which otherwise are essentially reluctant towards F-nucleophilic addition, now readily participate in this fluoroallylation reaction. Furthermore, this strategy provides an elegant example for the generation, as well as functionalization, of α-CF3-substituted benzylic radical intermediates using cheap and readily available starting materials.
Angewandte Chemie, International Edition published new progress about Allylation (fluoro). 13788-92-6 belongs to class pyrazoles-derivatives, and the molecular formula is C9H7BrN2, Safety of 1-(4-Bromophenyl)-1H-pyrazole.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics