Synthetic Route of C9H9NO. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Biocatalytic Processes for the Synthesis of Chiral Alcohols. Author is Zheng, Gao-Wei; Ni, Yan; Xu, Jian-He.
A review. Recently, key advances in mol. biol. and protein engineering techniques have yielded more practical biocatalytic processes for the synthesis of chiral alcs. This chapter discusses these cases, which focusing on biocatalytic processes implemented on industrial scale or with a great industrial potential for the synthesis of chiral alcs. Apart from chem. approaches, various biocatalytic strategies have been developed, including the use of, for example, ketoreductases (KREDs), and lipases. Examples of enzymic processes for the production of chiral statin intermediates are discussed in the chapter, mainly focused on those with potential applicability or being applied on an industrial scale. It explores a few biocatalytic methods for the synthesis of optically pure Et 2-hydroxy-4-phenylbutyrate (HPBE), (S)-4-chloro-3-hydroxybutyrate ((S)-CHBE), 3-quinuclidinol, and 3-hydroxy-3-phenylpropanenitrile (HPPN). Optically pure halogen-substituted 1-henylethanols are an important class of chiral building blocks. Finally, the chapter describes some biocatalytic processes for the synthesis of optically active halogen-substituted 1-phenylethanols.
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Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics