Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1300746-79-5, is researched, SMILESS is F[C-](F)([Cu+]1[N]2=C3C4=[N]1C=CC=C4C=CC3=CC=C2)F, Molecular C13H8CuF3N2Journal, Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t, Angewandte Chemie, International Edition called A Broadly Applicable Copper Reagent for Trifluoromethylations and Perfluoroalkylations of Aryl Iodides and Bromides, Author is Morimoto, Hiroyuki; Tsubogo, Tetsu; Litvinas, Nichole D.; Hartwig, John F., the main research direction is copper trifluoromethylation perfluoroalkylation reagent preparation aryl iodide bromide.Computed Properties of C13H8CuF3N2.
Authors have isolated a trifluoromethylcopper(I) reagent ligated by 1,10-phenanthroline, [(Phen)CuRF] (RF = CF3 (1), CF2CF2CF3 (2)) that reacts with unprecedented range of aryl halides at room temperature to 50°. In comparison to current alternative methods for trifluoromethylation of aryl halides, this system reacts under much milder conditions, tolerates a wider range of functional groups, tolerates basic heterocycles, reacts with more hindered substrates, can be extended to perfluoroalkylation, and occurs with a low total cost of goods. On a more fundamental level, the high reactivity of complexes 1 and 2 with a broad range of iodoarenes demonstrates that a general catalytic perfluoroalkylation of aryl iodides is not limited by the reactivity of the trifluoromethylcopper intermediate.
If you want to learn more about this compound((1,10-Phenanthroline)(trifluoromethyl)copper(I))Computed Properties of C13H8CuF3N2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1300746-79-5).
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics