An article Atroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis WOS:000537136800001 published article about ACID; ALCOHOLS; LIGANDS in [Ye, Chen-Xi; Han, Feng; Xie, Xiulan; Ivlev, Sergei; Meggers, Eric] Philipps Univ Marburg, Fachbereich Chem, Hans Meerwein Str 4, D-35043 Marburg, Germany; [Chen, Shuming; Houk, K. N.] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA in 2020.0, Cited 29.0. Recommanded Product: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6
A transformation of fluxional into configurationally stable axially chiral N-arylpyrroles was achieved with a highly atroposelective electrophilic aromatic substitution catalyzed by a chiral-at-metal rhodium Lewis acid. Specifically, N-arylpyrroles were alkylated with N-acryloyl-1H-pyrazole electrophiles in up to 93 % yield and with up to >99.5 % ee, and follow-up conversions reveal the synthetic utility of this new method. DFT calculations elucidate the origins of the observed excellent atroposelectivity.
Welcome to talk about 67-51-6, If you have any questions, you can contact Ye, CX; Chen, SM; Han, F; Xie, XL; Ivlev, S; Houk, KN; Meggers, E or send Email.. Recommanded Product: 67-51-6
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics