Robinson, H; Stillibrand, J; Simelis, K; Macdonald, SJF; Nortcliffe, A in [Robinson, Henry; Stillibrand, Joe; Simelis, Klemensas; Nortcliffe, Andrew] Univ Nottingham, Sch Chem, GlaxoSmithKline Carbon Neutral Labs Sustainable C, Triumph Rd, Nottingham NG7 2TU, England; [Macdonald, Simon J. F.] GlaxoSmithKline, Med Res Ctr, Gunnels Wood Rd, Stevenage SG1 2NY, Herts, England published Iridium-catalysed C-H borylation of beta-aryl-aminopropionic acids in 2020.0, Cited 29.0. Category: pyrazoles-derivatives. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.
Iridium-catalysed catalytic, regioselective C-H borylation of beta-aryl-aminopropionic acid derivatives gives access to 3,5-functionalised protected beta-aryl-aminopropionic acid boronates. The synthetic versatility of these new boronates is demonstrated through sequential one-pot functionalisation reactions to give diverse building blocks for medicinal chemistry. The C-H borylation is also effective for dipeptide substrates. We have exemplified this methodology in the synthesis of a pan alpha(v)integrin antagonist.
Category: pyrazoles-derivatives. Welcome to talk about 67-51-6, If you have any questions, you can contact Robinson, H; Stillibrand, J; Simelis, K; Macdonald, SJF; Nortcliffe, A or send Email.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics