Adding a certain compound to certain chemical reactions, such as: 15802-80-9, name is 3-(tert-Butyl)pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 15802-80-9, Product Details of 15802-80-9
Reference Production Example 3-2 3-t-butyl-1H-pyrazole-1-ylmethanol The mixture of 1.28 g of 3-t-butyl-1H-pyrazole, 0.66 g of paraformaldehyde and 0.3 g of triethylamine was stirred at 130 C for 7 hours. After the reaction mixture was cooled to room temperature, acetone was added to the reaction mixture. The mixture was filtered. The filterate was concentrated under reduced pressure. Hexane was added to the residue, and then crystalline was formed. The crystalline was collected to obtain 1.07 g of 3-t-butyl-1H-pyrazole-1-ylmethanol. 1H-NMR(CDCl3,TMS,delta(ppm)):1.28(9H,s),5.50(2H,s),6.13(1H,s),7.46 (1H, s)
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-(tert-Butyl)pyrazole, and friends who are interested can also refer to it.
Reference:
Patent; Sumitomo Chemical Company, Limited; EP1710234; (2006); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics