Electric Literature of 35344-95-7, These common heterocyclic compound, 35344-95-7, name is 1H-Pyrazole-4-carbaldehyde, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A nucleophile (1 mmol)was added to a solution of compound 1 or 2 (1 mmol) in MeCN or EtOH(10 ml) and the mixture was stirred at room temperature for 30 min (foradducts with 1) or 2?24 h (for adducts with 2). The precipitated productwas filtered off, washed with the same solvent (5 ml) and dried in air to give beige or brown solid adduct.
Statistics shows that 1H-Pyrazole-4-carbaldehyde is playing an increasingly important role. we look forward to future research findings about 35344-95-7.
Reference:
Article; Starosotnikov, Alexey M.; Shkaev, Dmitry V.; Bastrakov, Maxim A.; Fedyanin, Ivan V.; Shevelev, Svyatoslav A.; Dalinger, Igor L.; Mendeleev Communications; vol. 28; 6; (2018); p. 638 – 640;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics