Introduction of a new synthetic route about 1,4-Dimethylpyrazole

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dimethylpyrazole, other downstream synthetic routes, hurry up and to see.

Synthetic Route of 1072-68-0, The chemical industry reduces the impact on the environment during synthesis 1072-68-0, name is 1,4-Dimethylpyrazole, I believe this compound will play a more active role in future production and life.

After phase separation, the organic phase was distilled to afford 170.1 g (1.3 mol) of 5-chloro-1,4-dimethylpyrazole of boiling point (120) 105 C. and a purity of 99.7% (GC) and 99.3 g (0.6 mol) of 3,5-dichloro-1,4-dimethylpyrazole of boiling point (15) 85 C. and a purity of 99.5% (GC). The yields of 5-chloro-1,4-dimethylpyrazole and 3,5-dichloro-1,4-dimethylpyrazole resulted in an overall yield of 95% based on 1,4-dimethylpyrazole.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dimethylpyrazole, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Merkle, Hans Rupert; Fretschner, Erich; US2004/102505; (2004); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics