Related Products of 37687-24-4, These common heterocyclic compound, 37687-24-4, name is Diethyl 3,5-pyrazoledicarboxylate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A solution of compound 2a (2 g, 9.43 mmol); K2CO3 (2.6 g, 18.86 mmol) and 1, 3 bromochloropropane (7.4 mL, 47.16 mmol) in acetonitrile (60 mL) was refluxed for 1 h. The reaction mixture was cooled; filtered and extracted with ethyl acetate (2 x 150 mL), dried over anhydrous sodium sulphate, filtered and the filtrate was evaporated to dryness to afford compound 3c (2.1 g, 67%). MS (ES+) m/z: 334.
The synthetic route of 37687-24-4 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Surase, Yogesh B.; Samby, Kirandeep; Amale, Sagar R.; Sood, Ruchi; Purnapatre, Kedar P.; Pareek, Pawan K.; Das, Biswajit; Nanda, Kamna; Kumar, Subodh; Verma, Ashwani K.; Bioorganic and Medicinal Chemistry Letters; vol. 27; 15; (2017); p. 3454 – 3459;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics