In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 139756-02-8, name is 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Product Details of 139756-02-8
To a 250 ml three-mouth bottle by adding 2 – ethoxy formaldehyde 7.63 g, 1 – methyl -3 – propyl -4 – amino pyrazole -5 – carboxamide 9.6 g and isopropyl alcohol 150 ml, stir at room temperature 3 hours; adding 8.56 g anhydrous ferric trichloride, stirring which separate the reaction system access oxygen, temperature 60 C reaction 3 hours; boil off isopropanol about 100 ml, adding 180 ml purified water, filtered, drying to obtain the solid 14.8 g. Yield: 92.8%.
The synthetic route of 139756-02-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guangzhou Tongjuan Pharmaceutical Technology Co., Ltd.; Zheng Qingquan; Huang Shifu; Cao Xutao; Li Yongjian; (10 pag.)CN104804003; (2017); B;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics