Reference of 1572-10-7, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1572-10-7 as follows.
General procedure: The corresponding amine (10 mmol) and aldehyde (20 mmol) were dissolved in absolute ethanol (40 mL) and a catalytic amount of acetic acid added. The mixture was refluxed for 72 h. The crude product was isolated from the reaction solution by precipitation with diethyl ether and recrystallization from hot methanol.
According to the analysis of related databases, 1572-10-7, the application of this compound in the production field has become more and more popular.
Reference:
Article; Adamski, Ariel; Kruszka, Dariusz; Dutkiewicz, Zbigniew; Kubicki, Maciej; Gorczy?ski, Adam; Patroniak, Violetta; Tetrahedron; vol. 73; 24; (2017); p. 3377 – 3386;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics