152120-54-2, name is tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. category: pyrazoles-derivatives
General procedure: A mixture of 62a (30 mg), N,N’-bis(tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine (11) (48 mg), diisopropylethylamine (0.02 mL) and CH2Cl2 (0.6 mL) was stirred at room temperature for 12 h under a nitrogen atmosphere. The solvent was removed in vacuo. The residue was purified by flash column chromatography over silica gel with CHCl3/MeOH (10:1) as an eluent to give 63a (47 mg, 100%) as a colorless powder.
The synthetic route of 152120-54-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Inoue, Takayuki; Morita, Masataka; Tojo, Takashi; Nagashima, Akira; Moritomo, Ayako; Imai, Keisuke; Miyake, Hiroshi; Bioorganic and Medicinal Chemistry; vol. 21; 9; (2013); p. 2478 – 2494;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics