In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37687-24-4, name is Diethyl 3,5-pyrazoledicarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. HPLC of Formula: C9H12N2O4
reparation of intermediate 11-7; To a solution of diethyl 3,5-pyrazoledicarboxylate (1 g, 4.712 mmol) in acetone (20 ml), 2-bromo-3′-methoxyacetophenone (1.079 g, 4.712 mmol) and potassium carbonate (0.716 mg, 5.184 mmol) were added. The reaction mixture was stirred at RT 12h. The solvent was evaporated and residue was dissolved in DCM and washed with water. The organic phase was dried over Na2S04 and concentrated in vacuo. The residue, a yellow oil, (1.605g, 95% yield) was used in the next reaction step without further purification as intermediate II-7.
The synthetic route of 37687-24-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO); PASTOR FERNANDEZ, Joaquin; MARTINEZ GONZALEZ, Sonia; ALVAREZ ESCOBAR, Rosa Maria; RODRIGUEZ HERGUETA, Antonio; MARTIN HERNANDO, Jose Ignacio; RAMOS LIMA, Francisco, Javier; WO2011/89400; (2011); A1;,
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