Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1082745-50-3, name is 5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide, This compound has unique chemical properties. The synthetic route is as follows., Formula: C9H14N4O2
To a solution of 5-amino-1-tetrahydropyran-4-yl-pyrazole-4-carboxamide (4.78 g, 22.7mmol) in dry THF (200 mL) was added methyl 2-(4-bromophenyl)acetate (7.81 g, 34.1 mmol) and t-BuOK (1 M, 45 mL) in THF (45 mL). The mixture was stirred at 80C for 16 hours. Themixture was quenched with water (30 mL) and adjusted with HCI (iN, aqueous) to pH=7. The mixture was filtered. The filter cake was washed with water (20 mL x 3) to give 6-[(4- bromophenyl)methyl]-1-tetrahydropyran-4-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one (5 g).
According to the analysis of related databases, 1082745-50-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; H. LUNDBECK A/S; KEHLER, Jan; RASMUSSEN, Lars, Kyhn; LANGGARD, Morten; JESSING, Mikkel; VITAL, Paulo, Jorge, Vieira; JUHL, Karsten; (87 pag.)WO2018/73251; (2018); A1;,
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