Brief introduction of 1,3-Dimethyl-1H-pyrazol-4-amine

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 64517-88-0, its application will become more common.

Some common heterocyclic compound, 64517-88-0, name is 1,3-Dimethyl-1H-pyrazol-4-amine, molecular formula is C5H9N3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Safety of 1,3-Dimethyl-1H-pyrazol-4-amine

[7]; DMA was used as the reaction solvent. The reaction product was purified by trituration in a saturated aqueous sodium bicarbonate solution. The resultant solid was isolated, washed with water and dried under vacuum. The product gave the following characterising data :- 1HNMR Spectrum: (DMSOd6) 1.45 (t, 3H), 2.12 (s, 3H)5 3.69 (s, 3H)5 3.81 (s, 3H)5 3.84 (q, 2H)5 4.29 (q5 2H), 6.84 (d, IH), 7.46 (d, IH)5 7.79 (d, IH)5 7.81 s, IH), 8.03 (d, IH), 8.73 (s, IH)5 8.74 (d, IH)5 9.52 (s, IH); Mass Spectrum: M+H+ 449.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 64517-88-0, its application will become more common.

Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/113548; (2007); A1;,
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