Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 176969-34-9, name is 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid, A new synthetic method of this compound is introduced below., Safety of 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
Example 6 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid chloride 3-(difluoromethyl)-1-methyl-1H-pyrazol-4-carboxylic acid obtained by example 5 is treated with oxalyl chloride (1,25 eq) in toluene, and a few drops of dimethylformamide are added. The mixture is concentrated under reduced pressure to yield the carboxyl chloride.
The synthetic route of 176969-34-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SOLVAY SA; JAUNZEMS, Janis; (39 pag.)WO2019/122164; (2019); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics