These common heterocyclic compound, 17827-61-1, name is Methyl 1-Methylpyrazole-3-carboxylate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. COA of Formula: C6H8N2O2
Step B: 1 -Methyl- lH-pyrazole-3-carboxamide (3)A solution of methyl l-methyl-lH-pyrazole-3-carboxylate (1.1 g, 7.9 mmol) in NuEta32Omicron (10 mL) was stirred for 2 h at room temperature. The solvent was evaporated to give the crude product which was used for the next step without further purification.
The synthetic route of Methyl 1-Methylpyrazole-3-carboxylate has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK SHARP & DOHME CORP.; KUDUK, Scott, D.; MCCOMAS, Casey, C.; REGER, Thoma, S.; QI, Changhe; WO2014/150114; (2014); A1;,
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