Electric Literature of 143426-52-2, The chemical industry reduces the impact on the environment during synthesis 143426-52-2, name is 1-(4-(Chloromethyl)phenyl)-1H-pyrazole, I believe this compound will play a more active role in future production and life.
3 mmol of the compound IIIe was dissolved in 25 mL of DMSO, followed by the addition of 8 mmol of sodium carbonate. To the solution was added thereto at room temperature, the solution was heated to 85 C for 20 hours.The reaction was quenched, the reaction was poured intoa beakercontaining 100 mL of water, extracted several times with ethyl acetate, dried over anhydrous sodium sulfate, and the mother liquor was evaporated to dryness under reduced pressure. The resulting residue was purified bycolumn chromatography to give the title compound Ie
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-(4-(Chloromethyl)phenyl)-1H-pyrazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Nantong University; Dai Hong; Shi Yujun; Yao Wei; Song Chan; Qian Hongwei; Wang Xianglong; Zhang Zhou; Han Xudong; (16 pag.)CN106946782; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics