Brief introduction of 15953-45-4

According to the analysis of related databases, 15953-45-4, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 15953-45-4, name is 5-Chloro-3-methyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 15953-45-4

(b) S-Chloropyrazole-S-carboxylic acidA mixture of 5-chloro-3-methylpyrazole (3.6 mmol; see step (a) above), water (6 mL) and fert-butanol (1.2 mL) was heated to 750C, after which KMnO4 (1.42 g, 9 mmol) was added. The mixture was stirred at 75 C overnight and filtered hot. The solids were washed with boiling water. The combined cooled filtrates were extracted with EtOAc, and the combined extracts washed with NaCl (sat., aq.), dried (MgSO4) and concentrated. The crude solid was recrystallised from EPO EtOAc/hexane/pentane to give the sub-title compound as white crystals (Yield:350 mg (67%)).1H-NMR (DMSO-d6, 400 MHz), delta 13.65 (br s, IH), 6.80 (s, IH)

According to the analysis of related databases, 15953-45-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; BIOLIPOX AB; WO2007/45868; (2007); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics