Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1613191-73-3, name is Allyl 3,5-diamino-1H-pyrazole-4-carboxylate, A new synthetic method of this compound is introduced below., Computed Properties of C7H10N4O2
[0464] To a suspension ofallyl3,5-diamino-1H-pyrazole-4-carboxylate 3 (1 g, 5.489 mmol) in DMF (5 mL) was added(Z)-2-chloro-3 -dimethy amino-prop-2-eny lidene ]-dimethy ammoniumhexafluorophosphate (1.683 g, 5.489 mmol), followedby triethylamine (722.1 mg, 994.6 f.LL, 7.136 mmol).The reaction mixture was heated to 60 C. for 4 hr. duringwhich time a solid slowly precipitated out of solution. Thebrown suspension was allowed to cool down to RT. The solidwas filtered, washed with water and dried under vacuum togive allyl 2-amino-6-chloro-pyrazolo[1,5-a]pyrimidine-3-carboxylate 4b as a brown solid (1.092 g, 72% yield).Step 2: 2-amino-6-chloro-pyrazolo[1 ,5-a ]pyrimidine-3
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Charrier, Jean-Damien; Davis, Christopher John; Fraysse, Damien; Etxebarria I Jardi, Gorka; Pegg, Simon; Pierard, Francoise; Pinder, Joanne; Studley, John; Zwicker, Carl; Sanghvi, Tapan; Waldo, Michael; Medek, Ales; Shaw, David Matthew; Panesar, Maninder; Zhang, Yuegang; Alem, Naziha; US2015/158872; (2015); A1;,
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